Brand name: Taxol ®,
alkaloid, taxane and antimicrotubule agent
Paclitaxel is available by prescription only
Taxol is available by prescription only
Paclitaxel (Taxol, Onxal
) was approved by
the US Food and Drug Administration (FDA) to treat metastatic
Taxol is used to treat the following cancers:
- head and neck
- lung cancer: non-small
cell lung cancer and small cell lung cancer
- melanoma (dangerous
form of skin cancer)
- Esophageal cancer (Cancer
of the Esophagus).
Taxol is sometimes used to treat other medical conditions; talk to your physician or pharmacist for more
Taxol is given by
injection into a vein
Basing on certain criteria such as your age, type of cancer being treated, and your body surface
, your physician will prescribe you the most effective dose to combat the disease. Even after you start the
treatment, your doctor may change the dosage depending on the response of your body to the medication.
Taxol is injected into a vein (intravenous injection) by an oncologist or health care professional qualified and
has experience in giving chemotherapy drugs. The drug should be administered in a hospital or health center
equipped for its preparation. Taxol is usually given once every 3 weeks over 3 hours.
Overdose: Taxol is given in hospital by
professionals; the risk of overdose is very difficult, but not impossible. Taxol overdose may cause a decrease
in the number of blood cells in your bone marrow, and lead to severe health problems and even death. Keep all
appointments with your doctor before, during, and after treatment with Taxol; regular checkups can help detect
abnormalities in early stage before they become serious health problems.
the fact that Taxol is
administered in hospital, it is difficult to miss a dose if you keep your doctor’s appointments. Therefore,
be present at each appointment to take all doses of Taxol prescribed by your doctor. Misusing any
chemotherapy drug can be fatal. If for some reasons you cannot be present for the treatment, contact your
oncologist before the date of the treatment.
Taxol or is not recommended under the following conditions:
Mechanism of action (MOA): Taxol belongs to antineoplastics, a
class of chemotherapy drugs that works by stabilizing the mitotic spindle (also called nuclear spindle, formation of protein fibers in the cytoplasm of a cell during cell
division), which slows or stops the growth of cancer cells.
Interactions: if you are taking Taxol, tell your
doctor before taking prescription or non prescription medications such as aspirin,
vitamins, nutritional supplements, and St. John's wort.
Some medicines may interact with Taxol and causes health problems. Tell your doctor or pharmacist if you
are taking any of these medications:
In addition to attacking
cells, Taxol may interfere with certain normal cells, causing a number of side effects in most
- hair loss
- nausea and
- loss of
or/and skin discoloration
in the hands or toes
If the side
effects above persist for weeks, contact your oncologist. In addition, contact your doctor if you experience any
of these symptoms:
diarrhea or constipation
bruising or bleeding
redness, or swelling at the injection site
signs: skin rash, fever, chills, cough, sore throat, etc.