Brand name: Paraplatin
Other name: CBDCA
Manufacturer / Distributor:
Paraplatin is available by prescription only
used in the treatment of the following cancers:
- head and neck
- bladder cancer
doctors may prescribe Paraplatin for other medical conditions not mentioned in this article if they believe it
will help. Talk to your doctor or pharmacist for more information.
Paraplatin given by infusion into a
Paraplatin comes in the form of sterile injectable solution containing 10 mg of Paraplatin per mL (10
), in vials of 5, 15 and 45 mL. Paraplatin should be administered only in hospital by specialists in oncology,
hematology, or by physicians experienced in the field of chemotherapy. In addition, Paraplatin requires special
monitoring throughout the treatment.
oncologist will consider your body surface area (BSA), characteristic of the tumor and the status of your
overall health to determine the most appropriate dosage to prescribe you. In general, the drug is injected into
a vein, through an intravenous site on the skin that has been sterilized, over a period of 15 to 60 minutes. The
injection can be repeated after four weeks depending on the reactions of your body.
Overdose: the fact that
Paraplatin is administered in hospital, the risk of overdose is greatly reduced; however, it is not impossible.
Paraplatin overdose increased the toxic effects of the medication, and cause severe headaches, malaise or life
threatening conditions. If you suspect that you are overdosed, contact your health care provider or visit a
and poison center
near immediately. Any negligence in chemotherapy overdose can lead to death.
is not indicated for patients who fall in the following conditions:
who are breastfeeding
to Paraplatin or its ingredients
reduction of the function of the bone marrow
of severe allergy to mannitol.
talk you to your doctor
before taking prescription or non-prescription medications such as
vitamins, nutritional supplements and St. John's Wort.
Paraplatin should not be associated with certain medications; they can alter the effects of the drug or increase
the risk of developing side effects. Consult your doctor before taking the following medicines:
an antiviral drug
a polyene antifungal drug
immune system inhibitor
Digoxin, a medication used in the treatment of several
chemotherapy used to stop the
growth of cancer cells
a medication used to treat
irregular heart beat
Barbiturates, depressant drug that causes relaxation and
, a drug
used to inhibit the production of
acid in the stomach
medication used to treat pain of
(Cytoxan), a medication of the
alkylating agent family used to treat a variety of cancers
effects: In addition
to stopping the growth of
cells, Paraplatin may also interfere with your healthy cells that multiply quickly, and cause adverse effects.
Common Paraplatin side effects include:
- hair loss
ringing or hearing
- nausea and
or tingling in the fingertips
- bowel disorders
(constipation or diarrhea)
- Formation of sores in
rare, Carboplatine can cause serious side effects which require immediate medical attention; contact your doctor
immediately if you experience any of these symptoms:
(temporary loss of
- shortness of breath or
- painful or difficulty
- yellowing of the skin
or eyes (jaundice)
bruising or bleeding
- skin disorders such as
rash, hives or itching
- Swelling of your arms,
feet, ankles, or lower legs.
1 - nlm.nih.gov,