Class: Hycamtin is
classified as an "topoisomerase 1 inhibitor
Manufacturer / Distributor:
Hycamtin is available by prescription only
Indications : Hycamtin is used to
cancer after failure of first
line or subsequent chemotherapy
cell lung cancer that has relapsed or metastasized after treatment with other chemotherapy
may also be prescribed for other medical conditions besides ovarian and small cell lung cancer; talk to your
doctor or pharmacist for more information on Hycamtin.
form: Hycamtin is given by injection into a vein
in general, your oncologist will consider your condition, the type
and severity of the cancer, and your body mass index to prescribe you an effective dosage of Hycamtin. If you are
taking other chemotherapy drugs, it may also play a role in the choice of the dosage. Usually, Hycamtin is injected
into a vein over 30 minutes. The drug is given once a day for 5 consecutive days, and then suspended for 16
days. The cycle is then repeated at least 3 times.
Depending on your body's reaction to
the medication, your oncologist may change the dosage. It is important to undergo the therapy completely.
Hycamtin should be administered with great care by oncologist or medical professional that have experience in
chemotherapy drugs. In addition, Hycamtin must be given in a hospital or a similar institution that has enough
equipment for its preparation.
Hycamtin overdose can cause decreased levels of white blood cells in the blood, which can be dangerous in fragile
patients. Although rare, an overdose of Hycamtin may also lead to kidney problems. If you think you have been given
an overdose or you experience abnormal symptoms, contact your doctor immediately.
fact that Hycamtin is administered in hospital, missing dose is basically difficult if you respect your doctor’s
appointments. Therefore, If for some reasons you cannot go to the hospital for the treatment, contact your
oncologist before the date you are scheduled for the injection. Do
not stay home because you are experience side effects; Hycamtin
cause side effects in most patients. Missing a session of the therapy can
affect the entire treatment.
: you may
not be to take Hycamtin if you have :
- low number of white
production of platelets
to Hycamtin or any of its ingredients
- severe liver failure.
Mechanism of action (MOA): Hycamtin belongs to the class of
chemotherapeutic drugs known as topoisomerase type 1 inhibitor. Normally, before a cell divides into two, its
DNA is copied and each daughter cell receives a copy. Hycamtin slows or stops growth of cancer cells by
interfering with their DNA material needed for reproduction.
talk you to your doctor before taking
prescription or non prescription medications.
Some medicines may affect the therapeutic effects of Hycamtin, or increase the risk of developing side effects.
Tell your doctor and pharmacist if you are taking any of these medications:
- All other chemotherapy
Side effects: while attacking
cells, Hycamtin also affects
healthy cells, which lead to, in certain patients, the following side effects:
- mouth sores
or back pain
fever or chills accompanied by cough or hoarseness.
If the side
effects above persist for weeks, contact your oncologist. In addition, contact your doctor if you experience any
of these symptoms:
bleeding or bruising
- fast or
tingling, or burning sensation in the hands or feet
problems: hives, rash, itching, etc.
breathing or swallowing
Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs.