Manufacturer / Distributor:
Eli Lilly and Company
Gemzar is available by prescription only
Gemzar is given
by injection into a vein
Indications : Gemzar is used in the treatment of the
advanced or metastatic non-small cell lung cancer
advanced or metastatic pancreatic
breast cancer or a breast cancer that relapses after chemotherapy.
can also be prescribed for other medical conditions not mentioned in this article; talk to your doctor or
pharmacist for more information.
Dosage: dosage of Gemzar recommended by your
doctor depends on the type of cancer being treated, the overall state of your health, and your body surface area
(BSA). If you are taking other medications it may also play a role in the choice of the dosage.
is given by injection into a vein. Usually, the drug is given intravenously once weekly over a period of 30
minutes. A week of rest is often recommended every four weeks for your body to adapt to the drug.
should be given in hospital or a health care center equipped for its preparation. Gemzar should be given only by
physicians or health professionals who have experience in cancer chemotherapy.
Overdose: as with any drug, Gemzar overdose can
be dangerous if it is high and long term. An overdose of Gemzar can damage your bone marrow, and lead to serious
infections. During the treatment and even months after, avoid anything that can weaken your immune system and
the risk of infection. If you think you have taken an overdose, contact your doctor or the poison control center
nearest you as soon as possible to reduce or prevent complications.
Gemzar is administered
in hospital, lack of dose is basically difficult if you keep all your doctor’s appointments. If for some reasons
you cannot be present at the hospital for the treatment, contact your physician before the date you are scheduled
for the injection. Do not stay home because you are experience side
Gemzar cause side effects in most patients. Missing a dose or session of the
therapy can affect the entire treatment.
Gemzar is contraindicated
or should be used with precaution in case of the following conditions:
to Gemzar or any
of its components
against yellow fever
with live attenuated vaccine or phenytoin.
Mechanism of action (MOA): c
ancer cells are unable to survive if they cannot divide rapidly; Gemzar selectively inhibits the synthesis of DNA
that allows the cells to divide, which slows or stops the growth of cancer cells.
talk to your doctor
before taking vitamins or nutritional supplements. Some medicines can affect the curative effects of Gemzar,
or increase the risk of developing side effects. Consult your doctor before taking these
- Ganciclovir, an antiviral drug
- Azathioprine, an immune system inhibitor
- Barbiturates, depressant drug that causes relaxation and
, a drug
used to inhibit the production of
acid in the stomach
medication used to treat pain of
vaccine, yellow fever vaccine, etc.
(Cytoxan, Cytoxan, Neosar, Procytox,
Revimmune), a drug used to treat several types of cancers
- Celecoxib, a non-steroidal anti-inflammatory drug (NSAID)
used in the treatment of osteoarthritis, rheumatoid arthritis, painful menstruation, colon and rectum
Side effects: while attacking
cells, Gemzar also affects
normal (healthy) cells, which lead, in certain patients, to the following side effects:
or darkening of the skin or nails.
If the side
effects above persist for weeks, contact your oncologist. In addition, contact your doctor if you experience any
of these symptoms:
red skin rash
urination or red urine
bruising or bleeding
of the feet or legs
of the skin or eyes
of the feet or ankles.