Other names: 2-Fluoro-ara-A Monophosphate,
2-Fluoro-ara AMP, FAMP
Manufacturer / Distributor:
Fludara is available by prescription only
form: Fludara is given through a vein (IV
Indications: Fludara is used in the treatment of
the following medical conditions:
lymphocytic leukemia (CLL), in
patients for whom other forms of treatment have not worked
- Indolent or low-grade non-Hodgkin's lymphomas
patients that have been unsuccessfully treated with other forms of treatment.
may also be prescribed for other medical conditions not mentioned in this article; talk to your doctor or
pharmacist for more information.
to determine an
effective dosage to combat the
cancer, your doctor will consider
your general health, whether you are taking other chemotherapy drugs or not, the severity of the tumor and your
body mass index. Basing on these criteria, you health care provider will recommend the dosage most capable of
fighting the tumor. It is important that you take the medication as indicated by your oncologist.
comes as a powder to be added to a medical fluid and injected intravenously. Usually, the appropriate dose is
taken once daily for five consecutive days, every 28 days. The injection takes about 30 minutes to be
can damage organs in your body. It is very important during the treatment that you drink plenty of water to help
your body get rid of the toxic effects of the drug. This helps prevent kidney problems and improve the curative
effects of the drug.
Fludara overdose can be dangerous. Even at normal dose, Fludara can lead to a decrease in white blood cells and
platelets, which can cause serious infections; therefore, avoid anything that might weaken your immune system and
the risk of infection while taking Fludara.
In addition, Fludara can also damage your nervous system, and lead to seizures, restlessness, and even coma. In
some patients, Fludara can cause lung damage, and other unpredictable life threatening health problems. During the
treatment, respect all appointments you have with your doctor. If you think you have taken an overdose, contact
your doctor or the poison control center nearest you as soon as possible.
is basically difficult to miss a dose of Fludara if you are present for your appointment. Do not neglect your
appointment; one missed dose of Fludara can
affect the entire treatment. If for some reasons you cannot be present at the hospital for the treatment,
contact your health care provider. Do not stay home because you are experience side effects; Fludara cause
adverse effects in most patients.
Fludara is contraindicated in the following conditions :
to Fludara or any of its constituents
with live attenuated vaccine
not recommended or should be used with caution in patients whose general condition is poor, mainly those
- Opportunistic infections.
Mechanism of action (MOA): Fludara is the antimetabolite; it
cells by inhibiting their growth and preventing them from multiplying.
efore beginning a Fludara treatment, tell your doctor about all medications you are taking, whether prescription or
non prescription. Talk to your doctor before taking vitamins and nutritional supplements. Contact your doctor
before using the following medications:
Fludara tends to cause adverse effects in most patients; the most common Fludara side effects include:
- rash or
If the side
effects above persist for weeks, contact your oncologist. In addition, see your doctor if you experience any of
pain or discomfort
- fast or
- yellowing of the skin
of the arms, hands, feet, ankles, or lower legs
pain or tingling in the hands, arms, feet, or legs.
nlm.nih.gov, Fludarabine Injection