Brand name: Femara®
Manufacturer / Distributor:
Femara is available by
Femara comes as a pill
to be taken by mouth
Indication: Femara is used to treat
in postmenopausal women. Femara is also used in the treatment of advanced breast cancer in post-menopausal women
who were treated unsuccessfully with anti-estrogen therapy. The
medication can be taken with no problem right after a surgical therapy,
therapy and/or chemotherapy.
Femara can also be prescribed for other medical conditions not mentioned in this article; talk to your doctor or
pharmacist for more information.
Dosage: to determine an effective dosage to
fight the cancer, your doctor will consider your health, other chemotherapy drugs you are taking, the severity
of the tumor and your body mass index (weight / size). Basing on these criteria, your physician will give
effective doses of femara capable of combating the cancer. It is
important to adhere to dosage recommended by your doctor; do not change or stop taking the medication if you
experience side effects.
Usually, Femara is recommended at a dose of 2.5 mg per day. You can take the drug with or without food, but taking
Femara after a meal reduces the risk of nausea or vomiting. It is important to take the medication around the same
time every day. Depending on your condition, your doctor may recommend you taking Femara for years. Even if you
feel better, it is necessary that you continue taking the drug. If for valid reasons you cannot continue the
therapy, talk to your doctor before taking any decision.
Storage: store femara at room temperature
(15-25 ° C), away from heat above 40 ° C, light and moisture. Keep the medication out of the reach of children. Femara
and all other medications should not be used beyond the expiration date printed on the container.
Overdose: as with any drug, Femara overdose may
be dangerous, mainly if taken for long term. An overdose of Femara can damage the bone marrow, and lead to a
life threatening decrease in white blood cells and/or in platelets. If you take an overdose, contact your doctor
or the poison control center nearest you to reduce or prevent complications.
always take Femara as
In case you forget to
take a dose, take the missed one as soon as you remember it. However, if it is almost time for your next
do not double the next dose to recover the missing, it can be dangerous. Contact your doctor or wait to go back to
your regular schedule. This applies not only to Femara but also any other drug.
contraindicated in the following conditions :
to Femara or any of its ingredients
women or women who may become pregnant
who are breastfeeding.
Mechanism of action (MOA): Femara is classed as an aromatase
inhibitor, a group of chemotherapy drugs commonly used in
treatment treatment . It reduces the production of estrogens by blocking aromatase, an
enzyme involved in their biosynthesis. The cells of breast cancer are hormone-dependent; they need estrogens to
multiply. The reduction of estrogen production can thus limit the proliferation of cancer cells and prevents the
tumor from growing or developing.
before starting a treatment with Femara, tell your doctor about all medications you are taking, whether
prescription or non prescription. Talk to your doctor before taking vitamins, nutritional supplements or any herbal
medications such as hormone replacement therapy and hormonal contraceptives (birth control pills, patches, rings,
and injections), tamoxifen (Nolvadex), and raloxifene (Evista) can
affect the therapeutic property of Femara, or increase the risk of developing side effects; contact your doctor
before using them.
Femara cause adverse effects in most patients; common Femara side effects include:
- loss of
- rash or
- pain or
redness, warmth in the face and neck
If the side
effects above persist for weeks, contact your oncologist. In addition, contact your doctor if you experience any
of these symptoms:
- chest pain
- Persistent cough.
santecheznous.com, Quels sont les effets secondaires possibles de ce médicament ?
- nlm.nih.gov, Side
effects : Letrexole