Brand name: Aromasin
is available by prescription only
is used in the adjuvant treatment of postmenopausal women who have an early stage hormone-sensitive breast cancer,
and who received two to three years of tamoxifen. Exemestane is recommended to be taken as an adjuvant hormonal
therapy for five consecutive years.
Exemestane can also be used to treat advanced breast
in postmenopausal women for whom treatment with tamoxifen does not work effectively.
Note: Exemestane can be used to treat
other medical conditions in addition to breast cancer; talk to your doctor or pharmacist for more information.
form: Exemestane comes in tablet form to be
taken by mouth
1 tablet of Exemestane
daily, at around the same time every day, is often prescribed. However, considering your weight, presence of
other medical conditions and taking of other drugs, you doctor can recommend you a different dosage that is
most appropriate to your condition. Take the medication after a meal. Even if you feel better, it is
important to take Exemestane as recommended by your doctor or pharmacist. Do not take less of it; this can
reduce its healing power and curative
all chemotherapy drugs
can cause serious health problems when overdosed. Contact your doctor or a local poison control center near you
immediately if you experience symptoms indicating Exemestane
overdose. Do not neglect to see your physician; an overdose
of Exemestane can
lead to death.
Missing dose: i
n case you forget to take a dose of Exemestane
, take the missed one
as soon as you remember if it is not almost times for the following dose; do not
double the next dose to recover the missed one; it can be dangerous. You can contact your doctor or wait to go back
to your regular schedule.
Exemestane is contraindicated for children and women who are:
- being treated with estrogen
- Allergic to Exemestane
or one of its constituents.
beginning a breast cancer treatment with
Exemestane, tell your doctor if you have any of these health problems:
- Severe liver
- chronic kidney
- Glucose and galactose
Mechanism of action (MOA):
Exemestane is an enzyme inhibitor that is used in the treatment of hormone-receptor-positive (or
estrogen-responsive) breast cancer. It works by reducing the amount of estrogen produced by the body which cancer
cells need to live.
combination of Exemestane
with carbamazepine (Carbatrol, Epitol, and Tegretol) and all treatments containing estrogens is not recommended.
The following drugs can affect the healing action of Exemestane, or increase the risk of side effects. talk to
your doctor before taking any of the following:
- Rifampin (Rifadin, in
Rifater, in Rifamate)
- hormone replacement
Hormonal contraceptives: birth control pills, patches, rings, and injections.
talk to your doctor before consuming any of the following:
- St John's wort.
effects: in the combat against breast
cells, Exemestane can bring good results; however, by attacking
cancer, the drug also affect healthy cells that multiply rapidly, which can cause adverse effects in most
patients. The most common Exemestane side effects include:
or joint pain
falling asleep or staying asleep.
Exemestane can cause
serious side effects which require immediate medical attention; contact your doctor immediately if you
experience any of these symptoms:
swallowing or breathing.