Manufacturer / Distributor:
Cosmegen is available by prescription only
Cosmegen is given
through a vein
Indications : Cosmegen is used, alone or
association with other anticancer drugs, to treat the following
- testicular cancer
- Soft tissue sarcoma.
is sometimes used to treat other medical conditions not mentioned in this article; talk to your pharmacist or
doctor for more information.
Dosage: Cosmegen is usually injected into a
vein through an intravenous site on the skin, which beforehand was sterilized. The drug can be administered
alone or in combination with other antineoplastic agents (also called cancer chemotherapy drugs, cytotoxic drugs). The dose recommended by your doctor varies depending
on your health in general, other drugs you are taking, type of cancer you have, and especially your weight and
height. The reactions of your body to the treatment can obligate your health care provider to modify or stop the
is usually administered in hospital or a center having sterilization equipment available for its preparation.
The drug must be prepared and administered by medical specialists in oncology or hematology or nurses
experienced in oncology. Although administered into a vein, the drug can leak into surrounding tissue, cause
health issues; special monitoring during the treatment is necessary.
Overdose: Cosmegen is administered
in hospital by professionals; the risk of overdose is very low. However, accidental overdose or administrative
mistake can happen. Cosmegen overdose can cause exaggerated immunosuppression (life threatening low immune
defense), and lead to severe or fatal infections. There is no specific treatment for Cosmegen overdose. The
treatment is symptomatic and close monitoring to avoid major complications.
Missing dose: the fact that Cosmegen is administered in hospital by professional, it is very difficult to
miss any dose if you are present at your doctor’s appointment. If for some reasons you cannot go to the hospital
for the treatment, contact your health care provider before the date schedule for the injection.
Cosmegen is not
recommended, or should be used with precaution in the following conditions:
or shortly after chickenpox or shingles
to cosmegen or one of its ingredients.
Mechanism of action (MOA): Cosmegen slows or stops the growth of
cancer cells in your body
by modifying the structure of their DNA.
Some substances may
interfere with the healing power of Cosmegen, or amplify its toxic effects. You should not take any
prescription or non prescription (including aspirin and vitamins) drugs during the treatment with cosmegen
without first consulting your doctor or pharmacist. Cosmegen should not be associated with vaccine against
yellow fever, phenytoin, or live attenuated vaccines. If Cosmegen is associated with radiation therapy, increased surveillance is strongly
Side effects: b
y attacking the cancer cells, Cosmegen also attacks normal cells, which can cause various side effects in most
patients. common Cosmegen include:
pain and diarrhea
cause serious side effects which require immediate medical attention; contact your doctor immediately if you
experience any of these symptoms:
- fever, which can be
accompanied with a persistent cough
- shortness of
- unusual bruising or
- dizziness or/and
of the skin or eyes
- swelling of your feet
and pain at the injection site.